What Is Extracellular Matrix Technology?

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What Is Extracellular Matrix Technology?

09:09 24 February in by Genevieve Scott
In today's world of veterinary surgical care, the term 'regenerative medicine' is hear more frequently than ever. Regenerative medicine refers to the replacement or regeneration of cells, tissue, or organs to restore or establish normal function. Until recently, the generally accepted approach to full restoration revolved solely around the use of stem cells, and stem cell therapy. As technology and research advance, treatments do as well. Now, full restoration of tissue in animals can be achieved through products that do not require complicated procedures or expensive equipment. The latest wave in veterinary regenerative medicine stems from a technology referred to as Extracellular Matrix (ECM), which is now readily available to all veterinarians, and can be found from a variety of sources including porcine small intestinal submucosa (SIS). 

Found in all animals, ECM is the surrounding environment to cells. It is a micro-environment that has both structural and functional roles, and while the composition varies by tissue, it is generally composed of collagen, proteins and growth factors.

Extracellular Matrix is an acellular bioscaffold that focuses on the environment cells need to regenerate rather than the cells themselves. By creating a natural environment that mimics the functionality of damaged tissue, an ECM bioscaffold will harness the potential of a patient's native cells to fully repair damaged tissue. 

Extensively researched and readily available in the human medical field, ECM is quickly gaining a strong following with veterinary surgeons. Used in thousands of patients, Extracellular Matrix has shifted the paradigm of veterinary surgical care with applications ranging from dermal injury and wound care, internal soft tissue repair, veterinary tissue graft, orthopedic applications, veterinary ophthalmology and more.  


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